MTHFR Endure
Physician Designed MTHFR Endure is a 'Vitamins & Minerals' supplement, an 'Other Combinations' type, targeting specific nutritional support. It features several ingredients at clinically studied dosages, including Vitamin B6 (25mg), Vitamin B12 (1000mcg), Pantothenic Acid (125mg), and Zinc (5mg). The product achieved an N+ Score of 68, earning a C- grade, indicating an average quality assessment. However, Folate, Choline, and N-Acetyl L-Tyrosine are noted as underdosed. With 10 total ingredients, this supplement may be considered by individuals looking for comprehensive B vitamin and mineral support.
About This Product
MTHFR Endure by Physician Designed is a vitamins & minerals supplement containing 10 active ingredients. It has earned an N+ Score of 68/100 (Grade C-).
Notable clinical-dose ingredients include Vitamin B6, Vitamin B12, Pantothenic Acid and 1 more.
N+ Score Breakdown
Are key ingredients present at clinically effective doses based on research?
Does the product include all expected ingredients for its supplement category?
Are individual ingredient amounts clearly disclosed without proprietary blends?
Does the formula include a breadth of beneficial compounds from multiple pathways?
Strengths
- +Fully transparent label with individual ingredient amounts disclosed
- +Broad ingredient diversity exceeding category norms
- +4 ingredient(s) at clinical dose levels
Weaknesses
- −No major weaknesses identified
Ingredient Analysis (10 ingredients)
| Ingredient | Amount | Dose Adequacy |
|---|---|---|
| Vitamin B6 | 25.000 mg | Optimal |
| Folate | 100.000 mcg DFE | Under |
| Vitamin B12 | 1000.000 mcg | Optimal |
| Pantothenic Acid | 125.000 mg | Optimal |
| Choline | 25.000 mg | Under |
| Zinc | 5.000 mg | Adequate |
| N-Acetyl L-Tyrosine | 50.000 mg | Under |
| N-Acetyl-L-Cysteine | 100.000 mg | N/A |
| L-Serine | 50.000 mg | N/A |
| Betaine Anhydrous | 80.000 mg | N/A |
Clinical ranges based on NIH ODS Fact Sheets and peer-reviewed research. Status indicates whether the amount meets evidence-based thresholds.





