Physician Designed

MTHFR Endure

C-
N+ Score68
Vitamins & MineralsServing: 2 Capsule(s)Type: Other Combinations

Physician Designed MTHFR Endure is a 'Vitamins & Minerals' supplement, an 'Other Combinations' type, targeting specific nutritional support. It features several ingredients at clinically studied dosages, including Vitamin B6 (25mg), Vitamin B12 (1000mcg), Pantothenic Acid (125mg), and Zinc (5mg). The product achieved an N+ Score of 68, earning a C- grade, indicating an average quality assessment. However, Folate, Choline, and N-Acetyl L-Tyrosine are noted as underdosed. With 10 total ingredients, this supplement may be considered by individuals looking for comprehensive B vitamin and mineral support.

About This Product

MTHFR Endure by Physician Designed is a vitamins & minerals supplement containing 10 active ingredients. It has earned an N+ Score of 68/100 (Grade C-).

Notable clinical-dose ingredients include Vitamin B6, Vitamin B12, Pantothenic Acid and 1 more.

N+ Score Breakdown

Ingredient Adequacy50/100

Are key ingredients present at clinically effective doses based on research?

Formula Completeness50/100

Does the product include all expected ingredients for its supplement category?

Label Transparency100/100

Are individual ingredient amounts clearly disclosed without proprietary blends?

Ingredient Diversity88/100

Does the formula include a breadth of beneficial compounds from multiple pathways?

Strengths

  • +Fully transparent label with individual ingredient amounts disclosed
  • +Broad ingredient diversity exceeding category norms
  • +4 ingredient(s) at clinical dose levels

Weaknesses

  • −No major weaknesses identified

Ingredient Analysis (10 ingredients)

IngredientAmountDose Adequacy
Vitamin B625.000 mgOptimal
Folate100.000 mcg DFEUnder
Vitamin B121000.000 mcgOptimal
Pantothenic Acid125.000 mgOptimal
Choline25.000 mgUnder
Zinc5.000 mgAdequate
N-Acetyl L-Tyrosine50.000 mgUnder
N-Acetyl-L-Cysteine100.000 mgN/A
L-Serine50.000 mgN/A
Betaine Anhydrous80.000 mgN/A

Clinical ranges based on NIH ODS Fact Sheets and peer-reviewed research. Status indicates whether the amount meets evidence-based thresholds.