SAMe from Ortho Molecular Products is an Other Combinations supplement focusing on mood and joint support. Each capsule provides 400.000mcg of Folate and 400.000mg of SAMe. The 400.000mcg dosage of Folate is at a clinically studied level, which may support SAMe metabolism. While SAMe is a key ingredient, the data does not specify if its dosage meets clinical thresholds for all intended uses. The product has an N+ Score of 63, earning a 'D' grade, indicating an average-tier product. It offers good label transparency with two ingredients and may be suitable for individuals seeking support for mood or joint health.
About This Product
SAMe by Ortho Molecular Products is a vitamins & minerals supplement containing 2 active ingredients. It has earned an N+ Score of 63/100 (Grade D).
This product features a fully transparent label with individual ingredient amounts disclosed, and key ingredients are present at clinically effective doses based on peer-reviewed research.
Notable clinical-dose ingredients include Folate.
N+ Score Breakdown
Are key ingredients present at clinically effective doses based on research?
Does the product include all expected ingredients for its supplement category?
Are individual ingredient amounts clearly disclosed without proprietary blends?
Does the formula include a breadth of beneficial compounds from multiple pathways?
Strengths
- +Key ingredients at clinically effective doses
- +Fully transparent label with individual ingredient amounts disclosed
- +1 ingredient(s) at clinical dose levels
Weaknesses
- −Missing several expected ingredients for its category
Ingredient Analysis (2 ingredients)
| Ingredient | Amount | Dose Adequacy |
|---|---|---|
| Folate | 400.000 mcg | Optimal |
| SAMe | 400.000 mg | N/A |
Clinical ranges based on NIH ODS Fact Sheets and peer-reviewed research. Status indicates whether the amount meets evidence-based thresholds.





